Academic Staff and Fellows

KITAMATSU Mizuki: Professor Doctor of Engineering; Department/Applied Chemistry　 Graduate school/Molecular and Material Engineering

This laboratory specializes in peptide chemistry and bio-organic chemistry. Our research efforts revolve around creating non-naturally occurring peptides and nucleic acids having new functions that are unavailable in natural peptides/proteins and nucleic acids.

A fragment peptide (B-9(66)) in trasncription factor p53 shows apoptotic activity.

Research Area	Chemical Biology, Peptide Chemistry
Teaching (Graduate Course)	Bio-Structural Materials Chemistry
Research Interests	Drug delivery system, Cell-penetrating peptides, Bioactive peptides, Medicinal chemstry, Peptide nucleic acids
Selected Publications	(1) Molecular Basis of Potent Antiviral HLA-C-restricted CD8+ T Cell Response to an Immunodominant SARS-CoV-2 Nucleocapsid Epitope Nat. Commun. 2025, 16, 8062, DOI:10.1038/s41467-025-63288-3 (2) Fluorescence Detection of DNA with a Single-base Mismatch by a T_m-Independent Peptide Nucleic Acid (PNA) Twin Probe Org. Biomol. Chem. 2025, 23, 6557-6563, DOI:10.1039/D5OB00873E (3) Localization of Epidermal Growth Factor Receptor-Mutations using PNA–DNA Probes in Clinical Specimens from Patients with Non-small Cell Lung Cancer Sci. Rep. 2025, 15, 11314-11323, DOI:10.1038/s41598-025-95081-z
Research and Achievements	Research theme：https://www.apch.kindai.ac.jp/laboratory/kitamatsu/research.html Achievement：https://www.apch.kindai.ac.jp/laboratory/kitamatsu/publications.html
Education (Undergraduate Course)	Doshisha University
Title of Thesis, Institute, Date	Conformationally-restricted peptide nucleic acids with pyrrolidine-rings in the main chains, Okayama University, Sep/2005
Message to Students	The more I learn, the more I realize I don't know. The more I realize I don't know, The more I want to learn.

Bio-Physical Chemistry Laboratory

E-mail	kitamatu（at）apch.kindai.ac.jp Note that this e-mail address has replaced the "@" with "(at)" to prevent spam. When e-mailing, replace the "(at)" with "@".
Laboratory URL	https://researchmap.jp/kit