Academic Staff and Fellows
- KITAMATSU Mizuki
- Associate Professor Doctor of Engineering
- Department/Applied Chemistry Graduate school/Molecular and Material Engineering
This laboratory specializes in peptide chemistry and bio-organic chemistry. Our research efforts revolve around creating non-naturally occurring peptides and nucleic acids having new functions that are unavailable in natural peptides/proteins and nucleic acids.
A fragment peptide (B-9(66)) in trasncription factor p53 shows apoptotic activity.
Research Area | Chemical Biology, Peptide Chemistry |
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Teaching (Graduate Course) | Bio-Structural Materials Chemistry |
Research Interests | Drug delivery system, Cell-penetrating peptides, Bioactive peptides, Medicinal chemstry, Peptide nucleic acids |
Selected Publications |
(1) A Fluorescent Complex with PNAs Modified by Boronic Acid and Its Ligand Detects Target RNA in Cells Chem. Lett. 2024, 53, upae169, DOI:10.1093/chemle/upae169 (2) Configuration of Two Cysteine Residues in a Ring within a Stapled Bim Peptide Affects the Secondary Structure and Apoptotic Activity Bioorg. Med. Chem. Lett. 2024, 112, 129915-129919, DOI:10.1016/j.bmcl.2024.129915 (3) BNCT Pancreatic Cancer Treatment Strategy with Glucose-conjugated Boron Drug Biomaterials 2024, 309, 122605-122621, DOI:10.1016/j.biomaterials.2024.122605 |
Research and Achievements | |
Education (Undergraduate Course) |
Doshisha University |
Bio-Physical Chemistry Laboratory
kitamatu(at)apch.kindai.ac.jp
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Laboratory URL |
https://www.apch.kindai.ac.jp/laboratory/kitamatsu/index.html |