Researchers

KAKIMI Kazuhiro

KAKIMI Kazuhiro
Professor/Senior Staff
Faculty Department of Medicine / Graduate School of Medical Sciences
Researchmap https://researchmap.jp/KazuhiroKakimi

Research Activities

Research Areas

  • Life sciences , Immunology

Research Interests

免疫細胞治療, 癌免疫, immuntoherapy, cancer immunology

Published Papers

  1. From Metastatic Gateways to Immune Reservoirs: Reframing Tumor-Draining Lymph Nodes in Perioperative Cancer Immunotherapy
    Kazuhiro Kakimi; Yukari Kobayashi; Koji Nagaoka
    Immuno  22, Jul. 2026 
  2. The Immunological Window in Oral Cancer: Integrating the Progenitor Exhausted T Cells/Terminally Exhausted T Cells Axis and Tumor-Draining Lymph Nodes into Oral and Maxillofacial Surgical Practice
    Kenichi Kumagai; Yoshiki Hamada; Akihisa Horie; Kazuto Hoshi; Kazuhiro Kakimi
    Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology  Jun. 2026 
  3. Mathematical modeling of immune counter-regulation predicts efficacy of fractionated CD8+ T cell dosing strategies.
    Hiroki Kasai; Koji Nagaoka; Artem Lysenko; Kazuhiro Kakimi; Tatsuhiko Tsunoda
    Scientific reports  30, Apr. 2026 

MORE

Books etc

  1. 必修!腫瘍免疫学 , 編集 北野滋久; 垣見和宏 , 腫瘍関連マクロファージ(TAM)と骨髄由来抑制細胞(MDSC) , 金原出版 , Apr. 2022
  2. がん免疫ペディア : 腫瘍免疫学・がん免疫療法の全てをまるごと理解! , 編集 吉村 清; 垣見和宏 , がん精巣抗原 , 羊土社 , Mar. 2022

MISC

  1. Visualization of Cell Secretion and Dynamic Analysis of Responsive Cells to Accelerate Cancer Immunology Research , YAMAGISHI Mai; YANG Zhuohao; NAGAOKA Koji; KURISU Yuto; SUZUKI Nobutake; YOTSUMOTO Satoshi; KAMATANI Takashi; TANAKA Masato; KAKIMI Kazuhiro; SHIRASAKI Yoshitaka , 日本がん免疫学会総会プログラム・抄録集 , 29th , 2025
  2. Decoding CTL Cytotoxicity via Real-Time Imaging of Granzyme B Secretion at the Single-Cell Level , YANG Zhuohao; YAMAGISHI Mai; NAGAOKA Koji; KURISU Yuto; SUZUKI Nobutake; YOTSUMOTO Satoshi; KAMATANI Takashi; FUNATSU Takashi; TANAKA Masato; KAKIMI Kazuhiro; SHIRASAKI Yoshitaka , 日本がん免疫学会総会プログラム・抄録集 , 29th , 2025
  3. Development of a Single-Cell Secretion Imaging Technique Using Optical Waveguide-Based Total Internal Reflection Fluorescence Illumination , YANG Zhuohao; 鎌谷高志; 鈴木信勇; 山岸舞; 足立匠; 長岡孝治; 垣見和宏; 黒田悦史; 船津高志; 佐久間臣耶; 小関泰之; 白崎善隆 , 応用物理学会学術講演会講演予稿集(CD-ROM) , 72nd , 2025

MORE

Patents

  1. ネオアンチゲン予測装置、ネオアンチゲン予測方法、およびプログラム , 山口 茂夫, 久好 哲郎, 垣見 和宏
  2. ネオアンチゲン予測装置等 , 山口茂夫、垣見和宏、久好哲郎 , 未登録/審査中のため記載なし
  3. ネオアンチゲン予測装置、ネオアンチゲン予測方法、およびプログラム , 山口 茂夫, 久好 哲郎, 垣見 和宏 , 特許第7599641号

MORE

Research Grants & Projects

  1. 日本学術振興会, 科学研究費助成事業, 組織因子標的ADCによる腫瘍免疫応答の制御機構の解明 , 近畿大学
  2. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Deciphering the mechanisms underlying spatiotemporal breakdown of T-cell responses in cervical lymph node metastasis of oral cancer , The University of Tokyo
  3. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Development of Next-Generation Cancer Immunotherapy through Comprehensive Elucidation of TMB-Independent Non-Canonical Neoantigens , Kindai University

MORE