Researchers

no image

MOTOZONO Chihiro
Research associate
Faculty Department of Medicine
Researchmap https://researchmap.jp/immunol1

Research Activities

Research Areas

  • Life sciences, Virology
  • Life sciences, Immunology

Published Papers

  1. N-terminal pyroglutamylation of an HLA-A24-restricted immunodominant epitope enhances SARS-CoV-2-specific T-cell responses
    Yoshiki Aritsu; Masahiro Kitabatake; Amiri Kurose; Hiroshi Hamana; Takeshi Nakama; Kyoko Yamada; Ryutaro Furukawa; Noriko Ouji-Sageshima; Atsushi Hara; Kaito Yasuike; Suzu Itami; Huanyu Li; Keiko Udaka; Hiroyuki Kishi; Takamasa Ueno; So Nakagawa; Toshihiro Ito; Norihito Kawashita; Mizuki Kitamatsu; Chihiro Motozono
    Frontiers in Immunology  17  27, Apr. 2026 
  2. A probiotic bacterium modulates antitumor γδ T-cell responses in lung cancer
    Yoshihiko Goto; Garry Dolton; Hannah Thomas; Théo Morin; Yuka Tajima; Kosuke Imamura; Shinya Sakata; Kentaro Oka; Atsushi Hayashi; Motomichi Takahashi; Takamasa Ueno; Takuro Sakagami; Yusuke Tomita; Andrew K. Sewell; Chihiro Motozono
    24, Mar. 2026 
  3. Position-5-Driven Reorientation of an Immunodominant HLA-A*24:02 SARS-CoV-2 Epitope Drives Universal T-cell Escape
    Takeshi Nakama; Aaron Wall; Garry Dolton; Li-Rong Tan; Hannah Thomas; Hiroshi Hamana; Yoshiki Aritsu; Toong Seng Tan; Mako Toyoda; Yoshihiko Goto; Huanyu Li; Mizuki Kitamatsu; Keiko Udaka; Yusuke Miyashita; Hiroyuki Oshiumi; Kimitoshi Nakamura; Yoji Nagasaki; Rumi Minami; Hirotomo Nakata; Pierre J. Rizkallah; Hiroyuki Kishi; Takamasa Ueno; Andrew K. Sewell; Chihiro Motozono
    JCI Insight  17, Mar. 2026 

MORE

MISC

  1. Cross-reactivity of HLA-A*24:02-restricted T-cell receptors towards SARS-CoV-2 mutations , 仲摩健; 浜名洋; LI Huanyu; 後藤由比古; 有津由樹; 豊田真子; TAN Toong Seng; 北松瑞生; 宇高恵子; 岸裕幸; 上野貴将; 本園千尋 , 日本ウイルス学会学術集会プログラム・予稿集(Web) , 70th , 2023
  2. Evaluation of T cell antigen recognition for peptides introduced unnatural amino acids , 有津由樹; 北松瑞生; TAN Toong Seng; 上野貴将; 本園千尋 , 日本化学会春季年会講演予稿集(Web) , 102nd , 2022
  3. Vaccine-elicited preferential induction of polyfunctional Th cells is associated with protection against acute retroviral infection , C. Motozono; S. Tsuji-Kawahara; S. Takamura; M. Miyazawa , EUROPEAN JOURNAL OF IMMUNOLOGY , 46 , 817 , 817 , Aug. 2016

MORE

Awards & Honors

  1. Mar. 2026, 熊本医学会, 熊本医学会奨励賞
  2. 2023, 日本エイズ学会, ECC山口メモリアルエイズ研究奨励賞
  3. 2022, 熊本大学, 令和4年度 熊本大学研究業績表彰者

Research Grants & Projects

  1. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Development of immune regulation for emerging and re-emerging infectious diseases by human T cell cross-reactivity , Kumamoto University
  2. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Development of immune regulation for emerging and re-emerging infectious diseases by human T cell cross-reactivity , Kumamoto University
  3. Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Development of HLA-independent T cell receptor-T cell therapy for innovative immunological cancer therapy , University of Toyama

MORE