Researchers

- MOTOZONO Chihiro
- Research associate
| Faculty | Department of Medicine |
|---|---|
| Researchmap | https://researchmap.jp/immunol1 |
Research Activities
Research Areas
- Life sciences, Virology
- Life sciences, Immunology
Published Papers
-
Repeated mRNA vaccination and breakthrough infection reveal durable dominance but diminishing recall of vaccine-induced CD8⁺ T-cell clones.
Peng Xu; Satoshi Ueha; Hiroyasu Aoki; Masahiro Kitabatake; Chen Mingyu; Shigeyuki Shichino; Atsushi Hara; Noriko Ouji-Sageshima; Toshihiro Ito; Chihiro Motozono; Kouji Matsushima
International immunology 16, Jan. 2026 -
Molecular basis of potent antiviral HLA-C-restricted CD8+ T cell response to an immunodominant SARS-CoV-2 nucleocapsid epitope.
Yoshihiko Goto; You Min Ahn; Mako Toyoda; Hiroshi Hamana; Yan Jin; Yoshiki Aritsu; Takeshi Nakama; Yuka Tajima; Janesha C Maddumage; Huanyu Li; Mizuki Kitamatsu; Hiroyuki Kishi; Akiko Yonekawa; Dhilshan Jayasinghe; Nobuyuki Shimono; Yoji Nagasaki; Rumi Minami; Takashi Toya; Noritaka Sekiya; Yusuke Tomita; Demetra S M Chatzileontiadou; Hirotomo Nakata; So Nakagawa; Takuro Sakagami; Takamasa Ueno; Stephanie Gras; Chihiro Motozono
Nature communications 16 (1) , 8062-8062, 28, Aug. 2025 -
A probiotic bacterium modulates antitumor γδ T-cell responses in lung cancer
Yoshihiko Goto; Garry Dolton; Hannah Thomas; Théo Morin; Yuka Tajima; Kosuke Imamura; Shinya Sakata; Kentaro Oka; Atsushi Hayashi; Motomichi Takahashi; Takamasa Ueno; Takuro Sakagami; Yusuke Tomita; Andrew K. Sewell; Chihiro Motozono
19, Jul. 2025
MISC
- Cross-reactivity of HLA-A*24:02-restricted T-cell receptors towards SARS-CoV-2 mutations , 仲摩健; 浜名洋; LI Huanyu; 後藤由比古; 有津由樹; 豊田真子; TAN Toong Seng; 北松瑞生; 宇高恵子; 岸裕幸; 上野貴将; 本園千尋 , 日本ウイルス学会学術集会プログラム・予稿集(Web) , 70th , 2023
- Evaluation of T cell antigen recognition for peptides introduced unnatural amino acids , 有津由樹; 北松瑞生; TAN Toong Seng; 上野貴将; 本園千尋 , 日本化学会春季年会講演予稿集(Web) , 102nd , 2022
- Vaccine-elicited preferential induction of polyfunctional Th cells is associated with protection against acute retroviral infection , C. Motozono; S. Tsuji-Kawahara; S. Takamura; M. Miyazawa , EUROPEAN JOURNAL OF IMMUNOLOGY , 46 , 817 , 817 , Aug. 2016
Awards & Honors
- 2023, 日本エイズ学会, ECC山口メモリアルエイズ研究奨励賞
- 2022, 熊本大学, 令和4年度 熊本大学研究業績表彰者
Research Grants & Projects
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Development of immune regulation for emerging and re-emerging infectious diseases by human T cell cross-reactivity , Kumamoto University
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Development of immune regulation for emerging and re-emerging infectious diseases by human T cell cross-reactivity , Kumamoto University
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Development of HLA-independent T cell receptor-T cell therapy for innovative immunological cancer therapy , University of Toyama