Researchers

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Faculty	Department of Medicine
Researchmap	https://researchmap.jp/takamatsu_shiro

2003/04 - 2009/03 , Osaka Metropolitan University, Faculty of Medicine,
2018/04 - 2022/03 , Kyoto University, Graduate School of Medicine,
2023/04 - 2024/03 , The University of Texas MD Anderson Cancer Center, The Department of Genomic Medicine,
2024/04 - 2025/06 , The University of Texas MD Anderson Cancer Center, The Department of Gynecologic Oncology and Reproductive Medicine,
2025/08 - Today , Kindai University Nara Hospital, Obstetrics and Gynecology,

Apr. 2026 - Today , Kindai University Hospital Department of Obstetrics and Gynecology Medical Lecturer/Assistant Professor
Aug. 2025 - Mar. 2026 , Kindai University Nara Hospital Obstetrics and Gynecology Medical Lecturer
Apr. 2022 - Mar. 2023 , Kyoto University Graduate School of Medicine Gynecology and Obstetrics Program-Specific Assistant Professor
Jun. 2016 - Mar. 2018 , Kindai University Hospital Obstetrics and Gynecology Hospital Assistant Professor
Apr. 2014 - May. 2016 , Osaka Red Cross Hospital Obstetrics and Gynecology Medical Doctor
Apr. 2012 - Mar. 2014 , Fukui Red Cross Hospital Obstetrics and Gynecology OGBYN Fellow
Apr. 2011 - Mar. 2012 , Kyoto University Hospital Obstetrics and Gynecology OGBYN Fellow
Apr. 2009 - Mar. 2011 , Koseikai Takeda Hospital Medical Residency Program Resident Doctor

A novel CDK12 inhibitor induces homologous recombination deficiency to enhance PARP inhibitor efficacy in uterine serous carcinoma
Shunsuke Kawahara; Mana Taki; Junzo Hamanishi; Shunsuke Ebara; Ryusuke Murakami; Kohei Hamada; Koichi Watanabe; Yuko Hosoe; Yuka Mise; Shiro Takamatsu; Taito Miyamoto; Rin Mizuno; Koji Yamanoi; Ken Yamaguchi; Hiroko Yamakawa; Nobuyuki Kakiuchi; Tsukasa Baba; Seishi Ogawa; Daisuke Morishita; Kosuke Yusa; Masaki Mandai
Molecular cancer therapeutics 2, Apr. 2026
Long read sequencing reveals novel genomic and epigenomic alterations in repetitive regions of high grade serous ovarian cancer
Shiro Takamatsu; Jian Li; Thomas Welte; Eleonora Khlebus; Veena Vuttaradhi; Allison Brodsky; Barrett Lawson; R. Tyler Hillman
Scientific Reports 15 (1) 30, Oct. 2025 , Refereed
卵巣類内膜癌および重複子宮内膜癌の遺伝子変異に基づいたクローン進展と不均一性の解析
芦原隆仁; 村上幸祐; 宮川知保; 貫戸明子; 高松士郎; 松村謙臣
日本婦人科腫瘍学会学術講演会プログラム・抄録集 67回 , 270-270, Jul. 2025

Telomere-to-Telomere Long Read Whole Genome Sequencing Provides Novel Insights into Ovarian Cancer Genomics , Shiro Takamatsu; Jian Li; Thomas Welte; Eleonora Khlebus; Veena Vuttaradhi; Allison Brodsky; Barrett Lawson; R. Tyler Hillman , AACR Annual Meeting 2025. Apr 25-30, 2025, Chicago, Illinois, USA. , 29, Apr. 2025
Identification of high-grade endometrioid-like serous carcinoma of the ovary through multi-omics analysis: JGOG3025-TR2 study , Shiro Takamatsu; R. Tyler Hillman; Kosuke Yoshihara; Tsukasa Baba; Muneaki Shimada; Hiroshi Yoshida; Hiroaki Kajiyama; Katsutoshi Oda; Masaki Mandai; Aikou Okamoto; Takayuki Enomoto; Noriomi Matsumura , SGO Annual Meeting 2024. March 16-18th, San Diego, California, USA.
Homologous recombination deficiency in the CCLE cell lines correlates with in vitro resistance to platinum agents and PARP inhibitors. , Shiro Takamatsu; Noriomi Matsumura , AACR Annual Meeting 2023. Apr 15-19th, 2023, Orlando, Florida, USA.

産婦人科領域における情報リテラシー-ビッグデータとバイオインフォマティクスの活用バイオインフォマティクスを用いた婦人科がんゲノム研究について , 高松士朗; 高松士朗 , 産婦人科の実際 , 73 , 8 , 2024
Discovery of ovarian high-grade endometrioid-type tumors through multi-omics analysis: JGOG3025-TR2 study , 松村謙臣; 高松士朗; 高松士朗; 高松士朗; ヒルマンタイラーR; ヒルマンタイラーR; ヒルマンタイラーR; 吉原弘祐; 馬場長; 島田宗昭; 吉田浩; 梶山広明; 織田克利; 万代昌紀; 岡本愛光; 榎本隆之 , 日本癌学会学術総会抄録集(Web) , 83rd , 2024
シングルセル遺伝子発現解析による卵巣高異型度漿液性癌の腫瘍微小環境および腫瘍内不均一性の解明 , 高松士朗 , 日本婦人科腫瘍学会雑誌(Web) , 41 , 2 , 2023

日本学術振興会, 科学研究費助成事業, 子宮体がん免疫療法の効果に関連する腫瘍微小環境の解析 , 京都大学
Japan Society for the Promotion of Science, Overseas Research Fellowships, Elucidation of somatic structural variants and homologous recombination deficien cy in ovarian cancer using long-read whole-genome sequencing , The University of Texas MD Anderson Cancer Center