Researchers

YAMAGIWA Yoshiro

YAMAGIWA Yoshiro: Associate Professor

Faculty	Department of Science / Graduate School of Science and Engineering
Researchmap	https://researchmap.jp/read0034081

Education and Career

Education

- 1981 , Osaka City University, Faculty of Science,
- 1981 , Osaka City University, Faculty of Science,
- 1983 , Osaka City University, Graduate School, Division of Natural Science,
- 1983 , Osaka City University, 理学研究科,

Research Activities

Research Areas

Life sciences, Bioorganic chemistry
Nanotechnology/Materials, Structural/physical organic chemistry

Research Interests

有機合成天然物生物活性ラジカルスカベンジャー抗HIV, anti-HIV, Radical scavenger, Natural product, Organic synthesis

Published Papers

Improved and Practical Synthesis of the Integrastatin Core
Yoshiro Yamagiwa; Nozomi Haruna; Hideki Kawakami; Kouichi Matsumoto
Bulletin of the Chemical Society of Japan 93 (8) , 1036-1042, 15, Aug. 2020 , Refereed
Inhibitory effects of cardols and related compounds on superoxide anion generation by xanthine oxidase
Noriyoshi Masuoka; Ken-ichi Nihei; Ayami Maeta; Yoshiro Yamagiwa; Isao Kubo
FOOD CHEMISTRY 166 , 270-274, Jan. 2015 , Refereed
2-Hydroxy-4-isopropylbenzaldehyde, a potent partial tyrosinase inhibitor
K Nihei; Y Yamagiwa; T Kamikawa; Kubo, I
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 14 (3) , 681-683, Feb. 2004 , Refereed

反応から学ぼう有機化学の基礎 , 柏村成史; 山際由朗; 末永勇作; 佐賀佳央; 松本浩一 , 三共出版 , Nov. 2010
はじめてみようスペクトル解析 : MS・FTIR・500MHz NMR , 柏村成史; 森田全律; 山際由朗; 村井義洋; 石船学; 峰松敏江 , 三共出版 , 2007

Conference Activities & Talks

(2PB-61)Synthetic studies of Cytonic Acids A and B , YAMASHITA Taiki; YAMAGIWA Yoshiro; NAKAGAWA Takayo , 日本化学会第97春期年会 , 17, Mar. 2017
(3PB-223)Synthetic study of Integrastatins , KAWAKAMI Hideki; SHIGEKAWA Yoya; YAMAGIWA Yoshiro , 日本化学会第96春期年会 , 26, Mar. 2016
(3PB-222)Total Synthesis of Integracins A and B , Fujita Atsushi; TAKAYAMA Yoshiko; MAEKAWA Takehiko; YAMAGIWA Yoshiro , 日本化学会第96春期年会 , 26, Mar. 2016

キサンチンオキシダーゼが触媒するスーパーオキシド生成反応のカルドールによる阻害 , 益岡典芳; 金口裕生; 二瓶賢一; 山際由朗; 久保伊佐夫 , 日本生化学会大会(Web) , 87th , 2T16P-14(2P-178) (WEB ONLY) , 14] , Oct. 2014
Molecular design of antifungal agents , Kubo, I; P Xiao; K Nihei; K Fujita; Y Yamagiwa; T Kamikawa , JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY , 50 , 14 , 3992 , 3998 , Jul. 2002
Summary:In a rational approach to the design of antifungal agents against Saccharomyces cerevisiae, a series of alkyl gallates (3,4,5-trihydroxybenzoates) were synthesized and assayed. Nonyl gallate (1) was found to be the most effective with a minimum fungicidal concentration (MFC) of 12.5 mug/mL (42 muM), followed by octyl gallate (2) With an MFC of 25 mug/mL (89 muM). These MFCs are little influenced by pH values. A time-kill curve study indicates that nonyl gallate exhibits fungicidal activity against S. cerevisiae, at any growing stage. The antifungal activity of nonyl gallate is due primarily to its ability to act as a nonionic surface-active agent (surfactant). The length of the alkyl group is not a major contributor but plays a role in eliciting the activity to a large extent, As far as alkyl gallates are concerned, their antimicrobial spectra and potency depend largely on the hydrophobic portion of the molecules.
Unique tetranuclear copper((]G0002[)) cluster and monomeric iron((]G0002[)), ((]G0003[)) complexes with a tris(imidazolyl) chelating ligand(共著) , Polyhedron , 18 , 15 , 2047 , 2053 , 1999