Personalized Pharmacotherapy

Research Project

• Clinical research aimed at solving clinical questions derived from a pharmacist's perspective
• Establishing a foundation for personalized pharmacotherapy based on genetic information
• Pharmacoepidemiological research using real-world data
• Establishing strategies for data-driven drug repositioning
• Research on Preventing Occupational Accidents and Maintaining Hygiene Using Ozone
• Research on the Impact of Medication in Breast Milk on Newborns and Infants
• Research on Sharing Medicine Stock Information in Times of Disaster
• Research and educational studies for resuscitation
• Pharmacokinetic studies in cancer chemotherapy regimens

Introduction

Characteristics such as age, gender, genetic information, organ function, lifestyle habits, preferences, and concomitant medications vary between individuals. These characteristics influence the degree of therapeutic effect and the occurrence of adverse events from pharmacotherapy, leading to individual differences. We are conducting research to ensure the appropriate administration of drug therapy, enabling the selection of optimal pharmaceuticals and dosages by considering patient characteristics.

We are researching solutions to significant yet often overlooked medical and pharmaceutical challenges. As a countermeasure against global pandemics, we are developing simple, effective, and environmentally sustainable disinfection methods using ozone, along with strategies to prevent occupational hazards for frontline workers such as healthcare professionals and firefighters. Additionally, we are establishing an evidence base grounded in real-world measurements to ensure that mothers can breastfeed safely and confidently while taking medication. Finally, to prevent the recurring disruptions in medical supplies during disasters, we are collaborating with the Cabinet Office's Disaster Health and Medical Welfare Information System (D24H).

In emergency care, various medications and specialized treatments are administered after the return of spontaneous circulation. We conduct research to examine changes in pharmacokinetics during resuscitation in order to contribute to the appropriate use of medications in emergency medicine. In addition, we evaluate educational methods for acquiring skills in basic life support procedures.
　Cancer chemotherapy regimens involve the simultaneous administration of multiple drugs, including supportive therapies to prevent adverse effects. We are conducting research to investigate their impact on pharmacokinetics so as to help determine optimal dosing.